NeuroUnit Biomarkers for Inflammation and Neurodegeneration

NUBIN is a collaboration between several departments of the VUmc for a common goal: the development of assays in body fluids useful for diagnosis and monitoring of neuroinflammatory and neurodegenerative diseases such as AD and MS.

Biobanking

The NUBIN Biobanks contain several collections:

1) Paired CSF, serum/plasma, DNA, MRI-scans and clinical measures of Alzheimer patients, patients with cognitive impairment and healthy controls. Size of the collection: samples from >1000 patients. 

2) Paired CSF, serum/plasma, DNA, MRI-scans and clinical measures of patients with Mutliple Sclerosis, inflammatory and non-inflammatory controls. Size of the collection: samples from >250 patients.

3) Serum from Multiple Sclerosis patients with extensive clinical data over several years of follow-up, annually collected. Size of the collection: samples from >360 patients.

4) Serum from Multiple Sclerosis patients before treatment with interferon and during two years of treatment. Size of the collection: samples from >300 patients.

click here for more information on NUBIN, its organisation, staff etc.